{"id":74,"date":"2018-03-08T20:37:48","date_gmt":"2018-03-08T20:37:48","guid":{"rendered":"https:\/\/frm2018.cme-congresses.com\/?page_id=74"},"modified":"2018-11-11T17:25:54","modified_gmt":"2018-11-11T17:25:54","slug":"program","status":"publish","type":"page","link":"https:\/\/frm2018.cme-congresses.com\/program\/","title":{"rendered":"Scientific Program"},"content":{"rendered":"

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Day 1, Friday, November 16, 2018<\/h3><\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n<\/td>\nGood morning \u2013 Welcome Coffee, served prior to the start of the day<\/em><\/td>\n<\/tr>\n
<\/td>\n8:30 a.m. \u2013 9:15 a.m.<\/td>\nOpening Session<\/td>\n<\/tr>\n
<\/td>\n8:30 a.m. \u2013 8:45 a.m.<\/td>\nWelcome and announcement of the “Young Investigator Award”
\nNorbert Gleicher<\/strong>, MD<\/em> and David F. Albertini<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n8:45 a.m. \u2013 9:15 a.m.<\/td>\nThe \u201cBreaking News\u201d lecture<\/strong>
\nUnderstanding translational dysfunction in fragile X-associated neural and reproductive disorders.*
\nEthan J. Greenblatt<\/strong>, PhD<\/em>
\n*this talk is based on Greenblatt & Spradling, Science 2018; 361;709-712<\/em><\/td>\n<\/tr>\n
<\/td>\n9:15 a.m. \u2013 11:15 a.m.<\/td>\nSession 1 \u2013 Plenary: Where our journey is leading to \u2013 Part I<\/strong>
\nChairs: David F. Albertini<\/strong>, PhD<\/em> and Norbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n9:15 a.m. \u2013 9:45 a.m.<\/td>\nBeyond tech support: What physics brings to biology
\nEric D. Siggia<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n9:45 a.m. \u2013 10:15 a.m.<\/td>\nManeuvering between ethical concerns and the desire to advance science
\nEli Y. Adashi<\/strong>, MD, MS, MA<\/em><\/td>\n<\/tr>\n
<\/td>\n10:15 a.m. \u2013 10:45 a.m.<\/td>\nIncreased mTOR activity in FMR1<\/em> knockout mice and premature recruitment of oocyte pool reversed with rapamycin
\nS. Zev Williams<\/strong>, MD, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n10:45 a.m. \u2013 11:15 a.m.<\/td>\nHow the FMR1<\/em> gene and the AKT\/mTOR signaling pathways potentially control folliculogenesis
\nJulia Rehnitz<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:15 a.m. \u2013 11:45 a.m.<\/td>\nCoffee Break, Poster Viewing & Visit the Exhibition<\/td>\n<\/tr>\n
<\/td>\n11:45 a.m. \u2013 12:45 p.m.<\/td>\nSession 2 \u2013 Plenary: Where our journey is leading to \u2013 Part II
\n<\/strong>Chairs: Neeta Singh<\/strong>, MD<\/em> and Zeev Shoham<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:45 a.m. \u2013 12:15 p.m.<\/td>\nA first step in growing human primordial follicles in vitro<\/em> to maturity in a multi-step culture system
\nEvelyn E. Telfer<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n12:15 p.m. \u2013 12:45 p.m.<\/td>\nCombining imaging and transcriptomics at single cell resolution to understand blastocyst formation
\nAnna-Katerina Hadjantonakis<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n12:45 p.m. \u2013 1:00 p.m.<\/td>\nGet your lunch “to-go”<\/td>\n<\/tr>\n
<\/td>\n1:00 p.m. \u20132:00 p.m.<\/td>\nLunch break debate \u2013 bring your lunch<\/em><\/strong><\/p>\n

Chair: Norbert Gleicher<\/strong>, MD<\/em><\/p>\n

How effective is egg freezing as a preventative treatment for young women in securing their ability to reproduce later in life?<\/p>\n

– Very effective: Nicole Noyes<\/strong>, MD
\n<\/em>
\n– Not very effective: Vitaly A. Kushnir<\/strong>, MD<\/em><\/td>\n<\/tr>\n

<\/td>\n2:00 p.m. \u2013 3:30 p.m.<\/td>\nSession 3 \u2013 Paradigm change I: Clarifying the significance of chromosomal abnormalities in human embryos<\/strong>
\nChairs: Evelyn E. Telfer<\/strong>, PhD<\/em> and Vitaly A. Kushnir<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n2:00\u00a0p.m. \u2013 2:30 p.m.<\/td>\nWhen chromosomal abnormalities are the norm
\nRajiv C. McCoy<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n2:30 p.m. \u2013 3:00 p.m.<\/td>\nExplaining the purpose of PGS\/PGT-A
\nNathan R. Treff<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n3:00 p.m. \u2013 3:30 p.m.<\/td>\nExplaining the shortcomings of PGS\/PGT-A
\nRaoul Orvieto<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n3:30\u00a0p.m. \u2013 4:00 p.m.<\/td>\nCoffee Break, Poster Viewing & Visit the Exhibition<\/td>\n<\/tr>\n
<\/td>\n4:00\u00a0p.m. \u2013 6:00 p.m.<\/td>\nSession 4 \u2013 Paradigm change II: Changing the thinking about PCOS<\/strong>
\nChairs: Nicole Noyes<\/strong>, MD<\/em> and Raoul Orvieto<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n4:00\u00a0p.m. \u2013 4:30 p.m.<\/td>\nWhy new diagnostic criteria for different PCOS phenotypes are urgently needed
\nRicardo Azziz<\/strong>, MD, MPH, MBA<\/em><\/td>\n<\/tr>\n
<\/td>\n4:30\u00a0p.m. \u2013 5:00 p.m.<\/td>\nUsing AMH to diagnose PCOS?
\nNeeta Singh<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n5:00 p.m. \u2013 5:30 p.m.<\/td>\nA surprisingly common new hypo-androgenic PCOS-like phenotype
\nNorbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n5:30 p.m. \u2013 6:00 p.m.<\/td>\nEvidence for existence of a pituitary-adrenal-ovarian axis that controls ovarian function
\nVitaly A. Kushnir<\/strong>, MD<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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Day 2, Saturday, November 17, 2018<\/h3><\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n<\/td>\nGood morning \u2013 Welcome Coffee, served prior to the start of the day<\/em><\/td>\n<\/tr>\n
<\/td>\n8:30 a.m. \u2013 10:30 a.m.<\/td>\nSession 5 \u2013 Plenary: Where our journey is leading to \u2013 Part III<\/strong>
\nChairs: Eli Y. Adashi<\/strong>, MD, MS, MA<\/em> and Ricardo Azziz<\/strong>, MD, MPH, MBA<\/em><\/td>\n<\/tr>\n
<\/td>\n8:30 a.m. \u2013 9:00 a.m.<\/td>\n“Sensing of the whole”: Morphodynamics of early embryo development
\nIlya Volodayev<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n9:00 a.m. \u2013 9:30 a.m.<\/td>\nGenomic evidence for the importance of inflammation on IVF outcomes
\nMarc-Andr\u00e9 Sirard<\/strong>, DMV, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n9:30 a.m. \u2013 10:00 a.m.<\/td>\nE2F1-mediated epigenetic mechanism in ovarian response controls FMR1<\/em> expression in human granulosa cells
\nJulia Rehnitz<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n10:00 a.m. \u2013 10:30 a.m.<\/td>\nWhat autologous stem cell transplants are effective in the treatment of refractory Asherman’s syndrome?
\nNeeta Singh<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n10:30 a.m. \u2013 11:00 a.m.<\/td>\nCoffee Break, Poster Viewing & Visit the Exhibition<\/em><\/td>\n<\/tr>\n
<\/td>\n11:00 a.m. \u2013 12:00 p.m.<\/td>\nSession 6 \u2013 Plenary: Where our journey is leading to \u2013 Part IV<\/strong>
\nChairs:\u00a0Marc-Andr\u00e9 Sirard<\/strong>, DMV,\u00a0PhD\u00a0<\/em>and Julia Rehnitz<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:00 a.m. \u2013 11:30 a.m.<\/td>\nTargeting mTOR signaling to preserve reproductive longevity
\nKara N. Goldman<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:30 a.m. \u2013 12:00 p.m.<\/td>\nCorrelating micropattern differentiation of mouse pluripotent stem cells with mouse embryos, to inform human embryo cell fate patterning
\nAnna-Katerina Hadjantonakis<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n12:00\u00a0p.m. \u2013 12:15 p.m.<\/td>\nGet your lunch “to-go”<\/em><\/td>\n<\/tr>\n
<\/td>\n12:15\u00a0p.m. \u2013 1:15 p.m.<\/td>\nLunch break debate \u2013 bring your lunch<\/em><\/strong><\/p>\n

Chair: David H. Barad<\/strong>, MD, MS<\/em><\/p>\n

When is the right time to refer a patient into egg donation?<\/p>\n

– Above the age 42 and\/or FSH 15.0-20.0 mIU\/mL: Eli Y. Adashi<\/strong>, MD, MS, MA
\n<\/em>
\n– It should always be the patients\u2019 choice: Norbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n

<\/td>\n1:15\u00a0p.m. \u2013 3:00 p.m.<\/td>\nSession 7 \u2013 Paradigm change III: Individualizing IVF practice for best outcome by age and functional ovarian reserve<\/strong>
\nChairs: Kara N. Goldman<\/strong>, MD<\/em> and Pasquale Patrizio<\/strong>, MD, MS<\/em><\/td>\n<\/tr>\n
<\/td>\n1:15 p.m. \u2013 1:35 p.m.<\/td>\nWhy follicles need adequate androgen levels
\nAndrea Weghofer<\/strong>, MD, PhD, MS, MBA<\/em><\/td>\n<\/tr>\n
<\/td>\n1:35 p.m. \u2013 1:55 p.m.<\/td>\nHow to supplement hypo-androgenic women correctly
\nNorbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n1:55 p.m. \u2013 2:15 p.m.<\/td>\nThe intra-follicular molecular biology mandating advancement of egg retrieval in some women
\nDavid H. Barad<\/strong>, MD, MS<\/em><\/td>\n<\/tr>\n
<\/td>\n2:15 p.m. \u2013 2:35 p.m.<\/td>\nHIER \u2013 Highly individualized egg retrieval
\nVitaly A. Kushnir<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n2:35 p.m. \u2013 2:55 p.m.<\/td>\nCarrying over individualization of care into the embryology laboratory
\nDavid F. Albertini<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n3:00 p.m. \u2013 3:30 p.m.<\/td>\nCoffee Break, Poster Viewing & Visit the Exhibition<\/em><\/td>\n<\/tr>\n
<\/td>\n3:30 p.m. \u2013 5:30 p.m.<\/td>\nSession 8 \u2013 Plenary: Hidden treasures discovered<\/strong>
\nChairs:\u00a0Andrea Weghofer<\/strong>, MD, PhD, MS, MBA <\/em>and David H. Barad<\/strong>, MD, MS<\/em><\/td>\n<\/tr>\n
<\/td>\n3:30 p.m. \u2013 4:00 p.m.<\/td>\nModelling human embryology in a dish
\nMijo Simunovic<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n4:00 p.m. \u2013 4:30 p.m.<\/td>\nCan tacrolimus treatment affect pregnancy outcomes in presence of maternal immune abnormalities?
\nFrederick W. K. Kan<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n4:30 p.m. \u2013 5:00 p.m.<\/td>\nAn immune clock that controls pregnancy
\nBrice Gaudilliere<\/strong>, MD, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n5:00 p.m. \u2013 5:30 p.m.<\/td>\nA new frontier in the IVF laboratory: Automatic vitrification of oocytes and embryos
\nPasquale Patrizio<\/strong>, MD, MS<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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Day 3, Sunday, November 18, 2018<\/h3><\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n<\/td>\nGood morning \u2013 Welcome Coffee, served prior to the start of the day<\/em><\/td>\n<\/tr>\n
<\/td>\n9:00 a.m. \u2013 10:30 a.m.<\/span><\/td>\nSession 9 – Plenary: Hot topics<\/strong>
\nChairs: Zeev Shoham<\/strong>, MD <\/em>and John Zhang<\/strong>, MD, MSc, PhD
\n<\/em><\/td>\n<\/tr>\n
<\/td>\n9:00 a.m. \u2013 9:30 a.m.<\/td>\nOogonial stem cells after all?
\nEvelyn E. Telfer<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n9:30 a.m. \u2013 10:00 a.m.<\/td>\nStem cells and in the treatment of human infertility
\nSherman J. Silber<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n10:00 a.m. \u2013 10:30 a.m.<\/td>\nNuclear transfer: History and potential application in human reproduction
\nJohn Zhang<\/strong>, MD, MSc, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n10:30 a.m. \u2013 11:00 a.m.<\/td>\nCoffee Break<\/em><\/td>\n<\/tr>\n
<\/td>\n11:00 a.m. \u2013 1:00 p.m.<\/strong><\/td>\nClosing Session: Most Interesting recent 2018 presentations and yet unpublished data<\/strong>
\nChairs: David F. Albertini<\/strong>, PhD<\/em> and Norbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:00 a.m. \u2013 11:20 a.m.<\/td>\nThe evolving potential translational importance of cumulin (GDF9: BMP15) treatments for female fertility
\nAritro Sen<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n11:20 a.m. \u2013 11:40 a.m.<\/td>\nDoes platelet-rich (autologous) plasma (PRP) \u201crejuvenate\u201d ovaries and endometrium?
\nAndrea Weghofer<\/strong>, MD, PhD, MS, MBA<\/em><\/td>\n<\/tr>\n
<\/td>\n11:40 a.m. \u2013 12:00 p.m.<\/td>\nHuman blastocysts of normal and abnormal karyotypes display distinct transcriptome profiles
\nFrederick L. Licciardi<\/strong>, MD<\/em><\/td>\n<\/tr>\n
<\/td>\n12:00 p.m. \u2013 12:20 p.m.<\/td>\nTransferring chromosomally \u201cabnormal embryos\u201d after PGS\/PGT-A: a worldwide survey of IVF centers by www.IVF-Worldwide.com<\/a>
\nPasquale Patrizio<\/strong>, MD, MS<\/em><\/td>\n<\/tr>\n
<\/td>\n12:20 p.m. \u2013 1:00 p.m.<\/td>\nThe FRMC Closing Lecture<\/strong>
\nWill human embryos fly and more?
\nAli H. Brivanlou<\/strong>, PhD<\/em><\/td>\n<\/tr>\n
<\/td>\n1:00 p.m.<\/td>\nClosing Remarks
\nNorbert Gleicher<\/strong>, MD<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/pages\/74"}],"collection":[{"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/comments?post=74"}],"version-history":[{"count":0,"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/pages\/74\/revisions"}],"wp:attachment":[{"href":"https:\/\/frm2018.cme-congresses.com\/wp-json\/wp\/v2\/media?parent=74"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}